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Wireless Devices For Medical Applications

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Wireless Devices For Medical Applications

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dc.contributor.author Ativanichayaphong, Thermpon en_US
dc.date.accessioned 2008-04-22T02:41:30Z
dc.date.available 2008-04-22T02:41:30Z
dc.date.issued 2008-04-22T02:41:30Z
dc.date.submitted November 2007 en_US
dc.identifier.other DISS-1884 en_US
dc.identifier.uri http://hdl.handle.net/10106/702
dc.description.abstract The deployment of medical electronics in healthcare plays a significant role to overcome many problems in disease treatment and diagnosis. For advanced applications, wireless solutions are preferred. The wireless technologies offer a new dimension of therapy or diagnosis, when wires are often bulky, unsafe, uncomfortable or even impossible to be deployed in some circumstances. The wireless communication devices can be categorized into two groups, active and passive, depending on the power sources operating electronics. The active devices draw powers from a battery, while the others harvest powers from external or internal sources. In this work, two medical applications are studied for pain management and gastroesophageal reflux diagnosis using active and passive wireless approaches, respectively. The pain management systems are based on neurostimulation and neurorecording principles. The system requires batteries in implants for wireless communication. The neurostimulation can significantly improve pain relief when used on carefully selected chronic pain patients. An integrated recording and stimulating system has been designed, developed and used in animal experiments. The system consists of miniature components to record neuronal signals from the spinal cord and to activate the stimulation in the brain wirelessly. The system is equipped with a feedback function and decision making capability to automatically activate the stimulation from the recorded signals. A wearable prototype was tested in anesthetized rats. The results show that, when suitable stimulation parameters are used, the brain stimulation inhibits neural responses which may cause pain. For gastroesophageal reflux diagnosis, a new method of wirelessly detecting reflux in esophagus was proposed. Based on passive telemetry using inductive links, impedance of the refluxates can be determined remotely. The impedance variation can be determined from either amplitude or frequency changes of the detected signals. Planar coils integrated with electrodes on flexible substrates have been fabricated for amplitude detection. A circuitry connected with the sensing electrodes has been built for frequency detection. The devices are characterized in acid and non-acid solutions including the experiments in animals. Both techniques were used in implantable sensors without a battery to distinguish air, water and acid reflux wirelessly with a reader. The design methodology can also be applied to other sensors to monitor physiological conditions in human body. en_US
dc.description.sponsorship Chiao, Jung-Chih en_US
dc.language.iso EN en_US
dc.publisher Electrical Engineering en_US
dc.title Wireless Devices For Medical Applications en_US
dc.type Ph.D. en_US
dc.contributor.committeeChair Chiao, Jung-Chih en_US
dc.degree.department Electrical Engineering en_US
dc.degree.discipline Electrical Engineering en_US
dc.degree.grantor University of Texas at Arlington en_US
dc.degree.level doctoral en_US
dc.degree.name Ph.D. en_US

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