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Advances In Helical Stent Design And Fabrication: Studies Of Stent Thermal Treatment, Stent Mechanical Properties, And Stent Interactions With A Simulated Plaque-laden Artery

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Advances In Helical Stent Design And Fabrication: Studies Of Stent Thermal Treatment, Stent Mechanical Properties, And Stent Interactions With A Simulated Plaque-laden Artery

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dc.contributor.author Welch, Tre Raymond en_US
dc.date.accessioned 2010-11-01T21:28:41Z
dc.date.available 2010-11-01T21:28:41Z
dc.date.issued 2010-11-01
dc.date.submitted January 2009 en_US
dc.identifier.other DISS-10339 en_US
dc.identifier.uri http://hdl.handle.net/10106/5104
dc.description.abstract Advancements in processing biomaterials have lead to the development of bioresorbable PLLA drug-loaded stents with different geometric configurations. To further advance the technology, systematic studies have been carried out. This dissertation consists of six specific aims: 1) To characterize the effects of thermal annealing on the mechanical characteristics of PLLA helical stent, 2) To characterize the mechanical characteristics of a PLLA double helix stent, 3) To characterize the physical and chemical properties of PLLA films impregnated with niacin and curcumin, 4) To characterize the mechanical interaction of expanded stent and vascular wall with both model simulation and experimental studies using PDMS phantom arteries, 5) To simulate the stent-plaque-artery interactions using computer models. Results and their significances in bioresorbable PLLA drug-loaded stents technology as well as clinical prospects will be presented. en_US
dc.description.sponsorship Chuong, Cheng-Jen en_US
dc.language.iso en en_US
dc.publisher Biomedical Engineering en_US
dc.title Advances In Helical Stent Design And Fabrication: Studies Of Stent Thermal Treatment, Stent Mechanical Properties, And Stent Interactions With A Simulated Plaque-laden Artery en_US
dc.type Ph.D. en_US
dc.contributor.committeeChair Chuong, Cheng-Jen en_US
dc.degree.department Biomedical Engineering en_US
dc.degree.discipline Biomedical Engineering en_US
dc.degree.grantor University of Texas at Arlington en_US
dc.degree.level doctoral en_US
dc.degree.name Ph.D. en_US

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