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A Geometric Inequality in Pharmacokinetics

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A Geometric Inequality in Pharmacokinetics

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dc.contributor.author Holyk, Jennifer en
dc.contributor.author Ghandehari, Mostafa en
dc.date.accessioned 2010-06-03T18:24:30Z en
dc.date.available 2010-06-03T18:24:30Z en
dc.date.issued 2006-02 en
dc.identifier.uri http://hdl.handle.net/10106/2355 en
dc.description.abstract The arithmetic-geometric mean inequality is used to give a lower bound for the average concentration in a two-compartmental model in pharmacokinetics. A geometric interpretation is given to relate concentration to the area of a rectangle as a function of time. Generalization to multi-compartmental models is discussed. Formulas for a variable dosage regimen are derived using concepts from engineering economy and mathematics of finance. en
dc.language.iso en_US en
dc.publisher University of Texas at Arlington en
dc.relation.ispartofseries Technical Report;353 en
dc.subject Two-compartmental model en
dc.subject Arithmetic-geometric mean inequality en
dc.subject Pharmacokinetics en
dc.subject Variable dosage regimen en
dc.subject.lcsh Pharmacokinetics Mathematics en
dc.subject.lcsh Pharmaceutical arithmetic en
dc.subject.lcsh Mathematics Research en
dc.title A Geometric Inequality in Pharmacokinetics en
dc.type Technical Report en
dc.publisher.department Department of Mathematics en

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