A Geometric Inequality in Pharmacokinetics

ResearchCommons/Manakin Repository

A Geometric Inequality in Pharmacokinetics

Show full item record

Title: A Geometric Inequality in Pharmacokinetics
Author: Holyk, Jennifer; Ghandehari, Mostafa
Abstract: The arithmetic-geometric mean inequality is used to give a lower bound for the average concentration in a two-compartmental model in pharmacokinetics. A geometric interpretation is given to relate concentration to the area of a rectangle as a function of time. Generalization to multi-compartmental models is discussed. Formulas for a variable dosage regimen are derived using concepts from engineering economy and mathematics of finance.
Date: 2006-02

Files in this item

Files Size Format View Description
MathTechReport353.pdf 349.0Kb PDF View/Open PDF

This item appears in the following Collection(s)

Show full item record


My Account


About Us